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Setmelanotide (Imcivree) licensed for the treatment of obesity caused by specific rare genetic conditions (including pro-opiomelanocortin [POMC] deficiency and leptin receptor deficiency)
Figure 6, Panel C, presents a forest plot of HRs ranked from the greatest to least reduction in all-cause mortality
But while this is true in specific cases, high-priced brand-name drugs represent a small minority of prescriptions filled
April 2021
In further support of this notion, GLP-1R agonists can still reduce food intake when the aversive pathways of the AP are inhibited
